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KMID : 0371019990320020228
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Journal of Preventive Medicine and Public Health
1999 Volume.32 No. 2 p.228 ~ p.235
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Male to Female Heterosexual Transmission of in Korea
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Go Un-Yeong
Kee Mee-Kyung
Choi Byeong-Sun
Kang Chun
Do Kyoung-Mee
Lee Ju-Hyun
Lee Joo-Shil
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Abstract
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Objectives: Despite the importance of human immunodeficiency virus(HIV) transmission through heterosexual contact, the features of heterosexual transmission has not been well studied in Korea. So we conducted a cross sectional study to determine the transmission rates in married couples and assess risk factors for male to female heterosexual transmission of HIV.
Methods: 169 HIV-infected males and their female sex partners were recruited from 1985 to June 1998. We examined female sex partner´s HIV infection status and interviewed male index partners and their female sex partners about demographic characteristics and sexual practices. We analysed heterosexual transmission rate by epidemiologic characteristics, disease status and sexual practices. And we assessment risk factors for HIV infection by univariate and multivariate analysis.
Results: 30 female sex partners were infected at enrollment, yielding an transmission rate of 17.8%. Among couples who had used condoms consistently none of female sex partners was infected with HIV. In univariate analysis the significant risk factors were full blown AIDS status (OR=4.1, 95% Cl: 1.49-11.43) and low CD4 T cell count of index partners at enrollment (OR=7.8, 95% Cl: 2.19-27.80). In multivariate analysis HIV-1 RNA levels was significantly risk factor when adjusted by DC4 T cell counts and mean sexual contacts per month (OR=19.2, 95% Cl: 1.03-357.59).
Conclusions: The risk of male to female heterosexual transmission increased with advanced stages of HIV infection in the index male partners.
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KEYWORD
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Heterosexual transmission of HIV, Transmission rate, Risk factors
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